Research Articles
Disarming Cancer: How a Tiny Engineered Peptide Helps Thwart a Key Cancer Pathway
Discover how selective peptide binders of RNF43 offer new hope for Wnt signaling inhibition in cancer treatment.
Cellular Bouncers: How Ubiquitin Ligases Control the Wnt Nightclub in Cancer
Explore how ubiquitin-dependent mechanisms control Wnt receptors in cancer development, focusing on RNF43 and ZNRF3 as key regulators in tumorigenesis.
Disarming Cancer's Master Switch: The Quest to Tame Rogue Wnt Signaling
How a clever new strategy of molecular jamming is taking aim at a notoriously undruggable pathway in cancer through novel peptides targeting the β-catenin/TBL1 complex.
The RNF43 Enigma: How a Tiny Gene Lights Up Colon Cancer's Dark Pathway
Exploring the critical role of RNF43 mutations in serrated colorectal neoplasia and their implications for cancer treatment.