Discover how α-Cyperone, a compound from Cyperus rotundus, targets TRIM24 protein to combat breast cancer development and chemotherapy resistance.
Discover how Pellino1 protein protects against severe acute pancreatitis by suppressing necroptosis and promoting RIP3 degradation.
Discover how selective peptide binders of RNF43 offer new hope for Wnt signaling inhibition in cancer treatment.
Discover how PROTAC-STAN, an AI-powered framework, is transforming targeted protein degradation to combat previously undruggable diseases through interpretable predictions.
Explore the revolutionary approach of PROTAC-based HDAC degradation in epigenetic cancer therapy, moving beyond inhibition to complete protein elimination.
Discover how scientists are using computer-designed DNA aptamers to disrupt cholera biofilms and combat antibiotic resistance through molecular dynamics simulations.
Explore how F-box proteins regulate ubiquitination and influence tumor immunity, with insights into research methods and therapeutic potential.
Explore how neurologic concussion biomarkers are transforming diagnosis through point-of-care testing, enabling faster and more accurate detection of traumatic brain injuries.
Explore how brain inflammation research is revealing new therapeutic targets for Alzheimer's disease through laboratory models and cutting-edge experiments.
Groundbreaking discovery reveals how UHRF1 phase separation drives prostate cancer progression through epigenetic mechanisms.