Research Articles
Optimizing diGly Peptide Immunoprecipitation: A Comprehensive Guide to Maximizing Yield for Ubiquitinome Analysis
This article provides a systematic guide for researchers and drug development professionals seeking to maximize the yield of diGly peptide immunoprecipitation for mass spectrometry-based ubiquitinome analysis.
Peptide vs. Protein Level Ubiquitination Enrichment: A Strategic Guide for Proteomics Research
This article provides a comprehensive analysis of peptide-level and protein-level enrichment strategies for profiling protein ubiquitination, a crucial post-translational modification.
TUBEs in Ubiquitin Research: A Comprehensive Guide to Enrichment, Applications, and Advancements
This article provides a comprehensive overview of Tandem-repeated Ubiquitin Binding Entities (TUBEs), a transformative technology for studying protein ubiquitination.
Decoding Ubiquitination: A Comprehensive Guide to SILAC in Quantitative Proteomics
This article provides a comprehensive overview of Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and its powerful application in studying ubiquitination.
Linkage-Specific Ubiquitin Antibodies: A Comprehensive Guide for Research and Therapeutic Development
This article provides a comprehensive overview of linkage-specific ubiquitin antibodies, essential tools for decoding the complex biological signals of ubiquitination.
High pH Reverse-Phase Fractionation for diGly Peptides: A Complete Guide to Deep Ubiquitinome Analysis
This comprehensive guide explores high pH reverse-phase fractionation as a powerful strategy for deep ubiquitinome analysis through diGly peptide enrichment.
Ubiquitin Remnant Motif Antibody Immunopurification: A Complete Guide for Proteomic Profiling
This article provides a comprehensive overview of ubiquitin remnant motif antibody immunopurification, a cornerstone technique for profiling the ubiquitinome through mass spectrometry.
Advanced K-ε-GG DiGly Peptide Enrichment Protocol: A Comprehensive Guide for Deep Ubiquitinome Analysis
This article provides a comprehensive guide to the K-ε-GG diGly peptide enrichment protocol, a cornerstone method for mass spectrometry-based ubiquitinome analysis.
Unlocking the Ubiquitinome: A Comprehensive Guide to DIA Mass Spectrometry for Researchers
Data-independent acquisition (DIA) mass spectrometry is revolutionizing ubiquitinome analysis by providing unprecedented depth, reproducibility, and quantitative accuracy.
The Ubiquitin-Proteasome System: From Molecular Mechanism to Therapeutic Application in Disease and Drug Development
This article provides a comprehensive exploration of the ubiquitin-proteasome system (UPS), a crucial pathway for intracellular protein degradation and regulation.