Research Articles
Cutting Cancer's Master Switch: How Repurposing Old Drugs Offers New Hope Against USP22
Exploring how drug repurposing targets USP22, a key protein in cancer progression and treatment resistance, offering new anticancer therapeutic approaches.
A Cellular Traffic Cop: How Two Drugs Team Up to Halt a Rogue Cancer
Discover how Imatinib and Bortezomib work together to reactivate the APC/Cdh1 complex in Blast Crisis CML, offering new hope for cancer treatment.
SEL1L: The Cellular Bouncer Turning the Tide Against Solid Tumors
Discover how SEL1L, a key cellular quality control protein, is emerging as a powerful tumor suppressor with therapeutic potential against solid tumors like triple-negative breast cancer.
The Cellular Balancing Act: How MDM2 and ARF Control the Guardian of the Genome
Explore the intricate regulation of p53 tumor suppressor by MDM2 and ARF through ubiquitination and nuclear export mechanisms in cancer biology.
Ubiquitin-Specific Proteases: Unlocking New Avenues to Overcome Cancer Drug Resistance
Exploring how Ubiquitin-Specific Proteases (USPs) drive cancer drug resistance and the promising therapeutic strategies targeting these molecular scissors.
The Cell's Double Agent: How a Cancer-Fighting Protein Tags the Cell's Skeleton for Destruction
Discover how BRCA1 protein's secret role in tagging microtubules for destruction enhances Taxol's cancer-fighting effectiveness
Beyond Destruction: The Surprising Dual Life of the Hakai Protein
Discover the fascinating dual roles of Hakai protein - from cellular destruction to mRNA regulation and its implications for cancer research.
The Double Agent: How a Classic Tumor Suppressor Reveals a New Face in Cancer Spread
Discover how DLC1, a classic tumor suppressor, reveals surprising RhoGAP-independent functions in cancer invasion and metastasis.
How a Cellular Guardian Fights HPV-Linked Throat Cancer
Discover how TRAF3 gene acts as a tumor suppressor in HPV-associated head and neck cancer, offering new hope for targeted therapies.
Cellular Guardians and Traitors: The Double Life of Apoptosis-Inhibiting Proteins
Explore the fascinating world of Inhibitor of Apoptosis Proteins (IAPs) - crucial regulators of cell death, inflammation, and cancer progression.