Research Articles
Claspin: The Genome's Guardian and Its Battle Against Cancer
Explore the fascinating role of Claspin protein in DNA replication, checkpoint signaling, and its implications in cancer development and treatment.
The Double-Edged Sword: How TRIM27 Shapes Our Health and Fuels Disease
Exploring the dual roles of TRIM27 in cancer, neurodegeneration, and immunity through its ubiquitination mechanisms.
The Invisible Shield: How HLTF and SHPRH Guard Our Genome Against Cancer
Exploring the roles of HLTF and SHPRH proteins in DNA damage repair and their implications in cancer prevention and treatment.
The p53 Orchestra: How Ribosomal Protein S27a Conducts Cellular Defense Against Cancer
Exploring how ribosomal protein S27a regulates p53's tumor suppression activities and its dual role in cancer progression.
Unlocking p53's Potential: The Gene Signature Predicting Cancer Drug Success
Discover how a 13-gene signature predicts response to MDM2 inhibitors in p53 wild-type cancers, enabling personalized therapy approaches.