Research Articles
The Cellular Scissors in Crisis: How a Tiny Molecular Tag Can Make or Break Cancer Treatment
Explore how ubiquitin and SUMO molecular tags regulate topoisomerase II stability and their crucial implications for cancer chemotherapy.
The Cellular Sabotage: How a Key Protein Helps Myeloma Cells Thrive
Discover how AGO2 protein plays a critical role in multiple myeloma cell growth and IMiD drug effectiveness in this groundbreaking cancer research.
The Cancer Switch: How a Tiny Gene Called USP22 Drives Tumor Growth and Spread
Explore the role of USP22 gene in cancer progression, prognosis, and potential therapeutic targeting in this comprehensive scientific overview.
The Cell's Ultimate Shredder: How the Ubiquitin-Proteasome System Shapes Health, Aging, and Cancer
Explore the fascinating world of the ubiquitin-proteasome system - the cellular machinery that controls protein degradation and its crucial role in neurodegeneration, aging, and cancer.
Nature's Hidden Weapon: How Plant Compounds From Traditional Medicine Are Revolutionizing Cancer Treatment
Discover how natural polyphyllins from Paris polyphylla fight cancer through multiple cell death pathways including apoptosis, autophagy, and mitophagy.
The Double-Edged Sword: How TRIM56 Fights Viruses and Influences Cancer
Explore the dual role of TRIM56 protein in antiviral immunity and cancer development, with detailed molecular mechanisms and therapeutic potential.
The KLHL Family: The Cellular Cleanup Crew Gone Rogue in Cancer
How tiny protein regulators in our cells hold the key to new cancer treatments. Explore the role of KLHL proteins in cancer development and progression.
The Cellular Tug-of-War: How a Tiny Protein Tames a Growth Giant
Discover how the HILI protein inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation in this groundbreaking cancer research.
The Cell's Garbage Disposal: How Targeting a Tiny Machine is Revolutionizing Medicine
Explore how targeting the proteasome pathway is transforming cancer treatment and opening new frontiers in medicine.
SENP1: The Molecular Master Switch in Cancer and a Promising New Therapeutic Target
Explore SENP1's role in cancer development, its molecular mechanisms, and promising therapeutic targeting strategies in this comprehensive scientific overview.