Research Articles
The Skp2 Switch: How a Single Protein Drives Aggressive Cancer
Discover how Skp2 protein overexpression drives aggressive myxofibrosarcoma and serves as a predictor of poor survival outcomes and potential therapeutic target.
Unlocking Cancer Immunotherapy: How Targeting a Single Protein Could Revolutionize Treatment
Discover how targeting S100A1 protein can overcome immunotherapy resistance and enhance anti-PD-1 efficacy in cancer treatment.
Molecular Pac-Man: A New Strategy to Devour Cancer's "Command Center"
Discover how bioPROTAC technology is targeting the 'undruggable' SOX2 protein in cancer cells by hijacking cellular disposal systems.
Disarming a Cellular Saboteur: A New Hope for Fighting Brain Cancer
How scientists are targeting a protein called TRIM11 to cripple glioblastoma, one of the most aggressive human cancers.
The Cellular Janitor: How a Tiny Enzyme Called USP32 Could Revolutionize Cancer Therapy
Explore the fascinating role of USP32, a deubiquitinase enzyme, in cellular regulation and its potential as a groundbreaking target for cancer therapy.
The Jekyll and Hyde of Cancer: Unlocking the Secrets of UCH-L1
Explore the dual role of UCH-L1 protein in cancer biology - acting as both oncogene and tumor suppressor in different cancer types.
The Cellular Shredder: How a "Quality Control" Glitch Sparks Tumors
Discover how rapid proteasomal degradation of mutant AIP proteins triggers tumor formation in hereditary cancer syndromes.
The Cellular Betrayal: How a Rogue Protein Hijacks Our Body's Cancer Defense
Discover how the SS18-SSX1 oncoprotein promotes cancer by hijacking the p53 tumor suppressor pathway through enhanced HDM2 stability.
The Double Agent in Our Cells: Unraveling the MDM2 Prognostic Puzzle in Cancer
Explore the complex role of MDM2 in cancer prognosis, from its relationship with p53 to therapeutic approaches and future research directions.
The Mouse Guard: How a Single Gene Swap Unlocks a Cancer-Fighting Army
Discover how genetic modification in glowing mice enables complete eradication of aggressive breast cancer through immune system activation.