Explore the fascinating role of Claspin protein in DNA replication, checkpoint signaling, and its implications in cancer development and treatment.
Discover how the OPTN-K489E mutation disrupts cellular balance and accelerates ALS progression through enhanced apoptosis, necroptosis, and autophagy pathways.
Exploring how cDNA libraries from frog testes reveal insights into the ubiquitin system and its role in cellular regulation and human health.
Discover how tristetraprolin (TTP) mediates radiation-induced TNF-α production in lung macrophages and its potential to revolutionize lung cancer treatment.
Discover how ubiquitin, a tiny protein, regulates the complex process of wound healing through ubiquitination, acting as a cellular maestro in tissue repair and regeneration.
Discover how scientists use transcript profiling to understand self-incompatibility in mandarins and create seedless varieties through advanced genetic research.
Discover how non-toxic fractions from Streptomyces hygroscopicus show promising antimalarial properties by targeting the PfMQO mitochondrial enzyme in malaria parasites.
Discover how hepatocyte-derived exosomes transport drug-modified proteins to immune cells, triggering idiosyncratic drug-induced liver injury (DILI).
Discover how Hepatitis B virus manipulates host protein interactions to create cellular dependencies and ensure its survival, with implications for new therapeutic approaches.
Discover how functional interaction network analysis is transforming cattle breeding by identifying key genes responsible for reproductive traits.