Research Articles
The Secret Weapons in Banana Sap: How Proteins Are Fighting a Deadly Fungus
Discover how proteomic analysis of banana xylem sap reveals resistance mechanisms against Fusarium oxysporum TR4, the deadly banana fungus threatening global production.
The p53 Puzzle: Decoding the Guardian's Secrets to Revolutionize Cancer Therapy
Exploring groundbreaking patents and therapies targeting the p53 protein to revolutionize cancer treatment.
The Metabolic Maestro: How PKM2 and Matrin 3 Orchestrate a Cancer Symphony
Exploring how PKM2 phosphorylates Matrin 3 to promote FOXC2-mediated tumorigenesis in cancer metabolism.
Unlocking Nature's Arsenal: How an Ancient Malaria Drug Targets Aggressive Ovarian Cancer
Discover how dihydroartemisinin (DHA), derived from ancient antimalarial plants, targets PDGFRα in aggressive ovarian cancer, offering new hope against this lethal disease.
Unlocking p53's Potential: The Gene Signature Predicting Cancer Drug Success
Discover how a 13-gene signature predicts response to MDM2 inhibitors in p53 wild-type cancers, enabling personalized therapy approaches.
Unlocking Cancer's Shape-Shifting Secret: How a Single Protein Pulls the Strings in Ewing Sarcoma
Discover how EWS-FLI1 orchestrates Ewing sarcoma plasticity through a post-translational modification cascade regulating FOXM1 stability.
The Cancer Drug That Could Rescue Brains: How Bortezomib Offers New Hope for a Rare Genetic Disorder
Discover how bortezomib, a cancer drug, shows promise in treating Niemann-Pick Type C disease by rescuing misfolded NPC1 proteins and reducing cholesterol accumulation.
Chemoprevention: Your Cells' Ultimate Chill-Out Pill?
Explore the revolutionary frontier of cancer chemoprevention - a strategy that helps your cells stay cancer-free through natural compounds and repurposed drugs.
MetaDegron: AI's Protein Prediction Powerhouse Reveals Cellular Recycling Secrets
Discover how MetaDegron's multimodal AI predicts cellular protein degradation signals (degrons) with unprecedented accuracy, opening new frontiers in drug discovery.
The Lethal Overdrive: How Supercharging Cancer Pathways Could Be Our Smartest Weapon Yet
Exploring how hyperactivating cancer pathways can be a novel synthetic lethality approach in oncology