Exploring how neuromelanin organelles transform from cellular protectors to toxic agents in Parkinson's disease pathology.
Coverage of the groundbreaking discoveries presented at the 6th International Multithematic Scientific Bio-Medical Congress in Cyprus, featuring Nobel Laureate Aaron Ciechanover and other leading researchers.
Discover how calycosin, a plant-derived flavonoid, inhibits renal cell carcinoma by targeting the MAZ/HAS2 signaling pathway.
Discover how dexmedetomidine (Dex) protects against myocardial ischemia-reperfusion injury by activating cellular autophagy through the PINK1/Parkin pathway.
Discover how inhibiting SUMOylation with TAK-981 reprograms immune defenses and transforms cancer treatment by awakening macrophage and NK cell functions.
How scientists turned a viral enzyme's sabotage of immune protein ISG15 into a powerful diagnostic tool for detecting infections.
Discover how the UBE4B-ITCH complex induces neuroblastoma cell death through K63/K48 branched polyubiquitination of Ku70 and c-FLIPL, enhancing HDACi-mediated apoptosis.
Discover how Fra-1 protein orchestrates muscle wasting in cancer cachexia through mitochondrial dysfunction and apoptosis pathways.
Exploring how precision vaccines are combating the $30 billion global problem of cattle tick infestations through innovative science.
Exploring the critical role of CUL3 E3 ubiquitin ligases in plant development, hormone regulation, and stress responses.