This article provides researchers, scientists, and drug development professionals with a complete methodological framework for preserving labile ubiquitin modifications during immunoprecipitation experiments.

This comprehensive guide explores high pH reverse-phase fractionation as a powerful strategy for deep ubiquitinome analysis through diGly peptide enrichment.

Accurate analysis of the cellular ubiquitinome is crucial for research in cancer, neurodegeneration, and drug development.

This review comprehensively examines the critical roles of E3 ubiquitin ligases in cancer development and progression.

This article provides a comprehensive comparison of HECT and RING E3 ubiquitin ligases, the key enzymes conferring specificity in the ubiquitin-proteasome system.

This article provides a definitive, step-by-step guide for researchers and drug development professionals on reliably detecting protein ubiquitination via immunoblotting.

This article provides a comprehensive comparison between ubiquitinomics and proteomics for researchers and drug development professionals engaged in cancer biomarker discovery.

This article provides a comprehensive overview of Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and its powerful application in studying ubiquitination.

This article provides a comprehensive synthesis of ubiquitin-like proteins (UBLs), exploring their conserved β-grasp fold structure, intricate enzymatic conjugation cascades, and profound evolutionary lineage tracing back to prokaryotic sulfur-transfer systems.

This article provides a comprehensive overview of linkage-specific ubiquitin antibodies, essential tools for decoding the complex biological signals of ubiquitination.

This review provides a comprehensive analysis of the ubiquitin activation cascade across diverse species, from prokaryotic antecedents to complex eukaryotes.

This article provides a comprehensive comparison of ubiquitin linkage-specific antibody performance for researchers and drug development professionals.