Research Articles
The Ubiquitin Switch: How a Molecular Tag Team Forces Cancer Cells to Self-Destruct
Discover how the UBE4B-ITCH complex induces neuroblastoma cell death through K63/K48 branched polyubiquitination of Ku70 and c-FLIPL, enhancing HDACi-mediated apoptosis.
The Secret Weapon Inside Salt-Tolerant Plants: How Ubiquitin Warriors Battle Salinity
Discover how ubiquitin-like modifiers help plants survive salt stress through protein recycling, signaling, and autophagy mechanisms.
The Dance of Destruction: How Protein Engineering Revealed Ubiquitin Ligase Flexibility
Exploring how protein engineering revealed the conformational flexibility of ubiquitin ligases in the ubiquitination process.
Flickin' the Ubiquitin Switch: How a Tiny Protein Orchestrates Life's Symphony
Explore how ubiquitin, a small regulatory protein, controls cellular processes through precise molecular switches in DNA repair, immune responses, and gene expression.
The Invisible Architect of Vision: How Ubiquitin Shapes Eye Health and Disease
Explore how the ubiquitin-proteasome system regulates ocular health and contributes to diseases like cataracts, glaucoma, and macular degeneration.
Decoding the Cell's Ubiquitin Language: How Chemical Tools Are Cracking a Biological Cipher
Exploring how chemical biology is unlocking the secrets of ubiquitination, the cellular 'kiss of death' that regulates protein fate and function.
The Ubiquitin Enigma: How a Tiny Protein in Silkworms Holds Keys to Cellular Secrets
Exploring the critical role of BmUBRPS27a ubiquitin protein in silkworm development, immunity, and silk production