Research Articles
The Cell's Master Janitor: How a Tiny Tag Dictates Life and Death in Your Cells
Explore the fascinating ubiquitin system - the molecular cleanup crew that controls protein degradation and regulates the cell division cycle through precise tagging mechanisms.
Cracking the Cell's Postal Code: How Chemical Synthesis of Ubiquitin Conjugates Is Deciphering Cellular Signals
Explore how chemical synthesis of ubiquitin conjugates is revolutionizing our understanding of cellular signal transduction and disease mechanisms.
The Ubiquitin Saboteur: How a Mutant Protein Slowly Strangles Brain Cells
Discover how a mutant form of ubiquitin progressively impairs proteasome function in a dose-dependent manner, contributing to neurodegenerative diseases like Alzheimer's and Parkinson's.
Cracking the Ubiquitin Code: How Mass Spectrometry Deciphers Cellular Messages
Discover how mass spectrometry is revolutionizing our understanding of ubiquitin signaling and its implications for treating diseases from cancer to neurodegenerative disorders.
Cracking the Cellular Clean-Up Code: How a Molecular Pac-Man Chooses Its Snack
Discover how scientists are unraveling the mysteries of ubiquitin C-terminal hydrolase-L3 and its role in cellular clean-up processes.
The Cellular Switch: How Ubiquitin and Molecular Scissors Regulate Your Enzymes
Discover how ubiquitin-fold proteins and JAMM/MPN+ metalloproteases create a sophisticated cellular regulation system that controls enzyme activity through reversible modification.
Trapping Ubiquitin: How Molecular Memories in Nanoparticles Could Revolutionize Medicine
Discover how nanoparticle-embedded cryogel traps with ubiquitin memories are revolutionizing protein separation and medical diagnostics through photosensitive covalent imprinting.
Catching Proteins in the Act: The Shape-Shifting Mystery of Ubiquitin
Discover how advanced mass spectrometry reveals ubiquitin's secret shape-shifting abilities through proline isomerization
Cracking the Cell's Recycling Code: The Hunt for Ubiquitin Tags
Explore how scientists decode the ubiquitin tagging system in cells using peptide-based immunoaffinity enrichment to understand cellular recycling mechanisms.
Cellular "Janitors" & "Assassins": How the Ubiquitin-Proteasome System Became a New Anti-Cancer Weapon
Explore how the ubiquitin-proteasome system, the cell's protein degradation machinery, is being targeted for innovative cancer therapies like proteasome inhibitors and PROTACs.