Research Articles
The Invisible Architect of Vision: How Ubiquitin Shapes Eye Health and Disease
Explore how the ubiquitin-proteasome system regulates ocular health and contributes to diseases like cataracts, glaucoma, and macular degeneration.
The Ubiquitin Switches: How F-Box Proteins Fuel Cancer's Drug Defenses
Exploring how F-box proteins drive cancer drug resistance through ubiquitin-proteasome system manipulation and potential therapeutic strategies.
Unlocking HIV's Hideout: How the Viral Protein Vpr Reshapes Epigenetics to Reignite Infection
Discover how HIV's Vpr protein hijacks host epigenetics to reactivate latent viral reservoirs, with implications for cure strategies.
Double Blockade: How Dual-Targeted Therapy is Outsmarting Aggressive Leukemia
Exploring the synergistic combination of FLT3 inhibitors and BH3 mimetics in treating FLT3-ITD Acute Myeloid Leukemia
The Silent Guardian: How Cells Shut Down Genes to Fix Broken DNA
Discover how BRD7 protein orchestrates transcriptional repression to enable DNA repair at active gene regions, a breakthrough in genome maintenance research.
Decoding the Cell's Ubiquitin Language: How Chemical Tools Are Cracking a Biological Cipher
Exploring how chemical biology is unlocking the secrets of ubiquitination, the cellular 'kiss of death' that regulates protein fate and function.
The Silent Cleanup Crew: How Autophagy Gone Wrong Sparks Animal Diseases
Exploring how dysfunctional autophagy contributes to neurodegenerative disorders, metabolic diseases, and inflammatory conditions in animals.
The Lipid Linchpin: How a Metabolic Mastermind Fuels Lung Cancer's Deadliest Cells
Exploring how SCD1's manipulation of cellular architecture through YAP/TAZ fuels lung cancer stem cells and drives recurrence.
The Hidden Conductor: How a Tiny RNA Steers Stem Cell Destiny
Discover how the lncRNA ESRG regulates TCF3 alternative splicing to maintain human embryonic stem cell pluripotency and self-renewal.
BAP1: The Unsung Hero in Lung Cancer's Molecular Battlefield
Exploring BAP1's role as a prognostic biomarker and therapeutic target in non-small cell lung cancer (NSCLC)