Research Articles
The Double Life of HIF-1α: How Cellular Survival Mechanisms Turn Traitor
Exploring how HIF-1α's survival mechanisms can become pathological when activated by TOR and SMAD pathways in cancer, autoimmunity, and fibrosis.
The Stealth Saboteur: How Pancreatic Cancer Hijacks Muscle Maintenance via IGFBP-3
Groundbreaking research reveals how tumor-derived IGFBP-3 drives muscle wasting in pancreatic cancer patients through metabolic hijacking.
Sabotaging the Sentinel: How Adenovirus Hijacks the Cell's DNA Damage Alarm
Explore how adenoviruses disrupt the cellular DNA Damage Response (DDR) pathway to enable viral replication, with implications for cancer therapy.
The Metastasis Breaker: How Silencing a Tiny Enzyme Could Halt Cancer's Spread
Groundbreaking research on SIAH2 inhibition as a promising approach to contain metastatic spread in treatment-resistant cancers.
The Evergreen Energy Revolution: Supercharged Switchgrass Takes Root
Discover how genetically modified switchgrass with elevated miR156 levels produces 250% more biomass while offering natural bioconfinement for sustainable biofuel production.
The Invisible Shield: How a Tiny Genetic Variation Shapes Health in Hispanic Populations
Discover how A20 (TNFAIP3) genetic variations impact inflammation and autoimmune disease risks in Hispanic populations through groundbreaking research.
Shattering Cancer's Defenses: The PROTAC Revolution Targeting MLK3
Discover how PROTAC technology is revolutionizing cancer therapy by targeting MLK3 in triple-negative breast cancer, offering hope against treatment-resistant tumors.
The PJA1 Puzzle: How Silencing a Tiny Enzyme Could Revolutionize Liver Cancer Treatment
Discover how silencing the PJA1 enzyme could revolutionize liver cancer treatment by restoring the TGF-β pathway's tumor-suppressing capabilities.
The Cell's Secret Sticker System: How SUMOylation Shapes Your Proteins
Explore the fascinating world of SUMOylation - a crucial post-translational modification that regulates protein function, cellular organization, and human health.
UNBS1450: Nature's Answer to Lung Cancer's Defense System
How the plant-derived molecule UNBS1450 disrupts NF-κB signaling in non-small cell lung cancer cells, overcoming chemotherapy resistance.