Research Articles
Disarming Cancer: How a Tiny Engineered Peptide Helps Thwart a Key Cancer Pathway
Discover how selective peptide binders of RNF43 offer new hope for Wnt signaling inhibition in cancer treatment.
Disrupting Cellular Conversations: How Scientists Are Intercepting the NEDD8-NAE Handshake
Explore how scientists are developing small molecules to disrupt the NEDD8-NAE protein-protein interaction, creating promising new approaches to cancer therapy.
Hunting Cancer's Kill Switch: How Computer Design and Lab Experiments Are Revolutionizing Cancer Therapy
Exploring the intersection of computational biology and laboratory research in developing protein ligands to induce apoptosis in cancer cells.
Copper's Double-Edged Sword: How Cuproptosis is Revolutionizing Cancer Therapy
Explore how cuproptosis, a newly discovered form of copper-induced cell death, is transforming cancer treatment approaches and offering new therapeutic possibilities.
Zapping Cancer with Plasma: How Ionized Gas Activates Our Cellular Defense System
Discover how non-thermal plasma therapy activates MUL1 E3 ligase to degrade AKT protein in head and neck cancer cells, offering a promising new cancer treatment approach.
Breaking Cancer's Shield: How Combining MDM2 Inhibition with ONC201 Attacks Resistant Tumors
Explore the revolutionary combination therapy of MDM2 inhibitors and ONC201 for treating solid tumors with MDM2 overexpression.
The Intracellular Assassin: How Scientists Are Engineering Smart Cancer-Killing Molecules
Discover how synthetic Granzyme B molecules are revolutionizing targeted cancer therapy through the innovative COVERT platform.
Cracking the Code: How Mathematical Models Guide Next-Generation Cancer Therapies
Explore how PK/PD modeling predicts BTK degrader efficacy in cancer treatment through mathematical correlation of drug exposure, protein degradation, and tumor growth inhibition.
A Trojan Horse for Brain Cancer: Doubling Down on Therapy with Smart Nanoparticles
Discover how immuno-nanoparticles deliver a dual-drug therapy to combat glioblastoma by overcoming the blood-brain barrier and targeting cancer cells with precision.
HSN-003839: Harnessing the Body's Cellular Recycling System to Target Cancer
Explore HSN-003839, a novel USP21 inhibitor showing promise in cancer therapy by targeting the ubiquitin-proteasome system.