Research Articles
Taming Cellular Chaos: How a Molecular "Tag" Guides a Master Regulator of Cell Division
Discover how SUMOylation controls Polo-like Kinase 1 (Plk1) nuclear import and stability, revealing new insights into cell division and cancer therapy.
Molecular Matchmakers: How Scientists Engineered a Key to Unlock a Cellular Mystery
Discover how scientists created a stable chemical SUMO1–Ubc9 conjugate to reveal the molecular mechanism of cellular protein tagging.
The Cell's Secret Sticker System: How SUMOylation Shapes Your Proteins
Explore the fascinating world of SUMOylation - a crucial post-translational modification that regulates protein function, cellular organization, and human health.
The SUMO Switch: How Blocking a Tiny Cellular Tag Could Revolutionize Cancer Therapy
Discover how inhibiting SUMOylation with TAK-981 reprograms immune defenses and transforms cancer treatment by awakening macrophage and NK cell functions.