Research Articles
Breaking the Vicious Cycle: How a Novel Drug Combination Fights Multiple Myeloma in the Bone Microenvironment
Discover how CC-292 and carfilzomib combination therapy targets both myeloma cells and bone destruction in multiple myeloma treatment.
Outflanking the Enemy: How Scientists Found a New Way to Attack Resistant Blood Cancer
Discover how scientists identified PIM2 as a critical survival pathway in multiple myeloma, revealing a novel therapeutic target to overcome carfilzomib resistance.
The 1q Amplification in Multiple Myeloma: A Genetic Key to More Aggressive Cancer
Understanding how 1q amplification drives aggressive multiple myeloma and the search for targeted therapies
Breaking the Shield: New Research on How Myeloma Cells Resist Treatment
Explore the molecular mechanisms of bortezomib resistance in multiple myeloma, including ferroptosis, exosomes, and the DEK gene pathway.
The Invisible Shield: Unraveling the Mystery of Proteasome Inhibitor Resistance in Multiple Myeloma
Exploring the cellular mechanisms behind proteasome inhibitor resistance in multiple myeloma and emerging strategies to overcome this challenge in cancer treatment.
Trapping the Enemy Within: How Nuclear Export Blockade is Revolutionizing Multiple Myeloma Treatment
Exploring the synergistic effects of selinexor and carfilzomib in targeting XPO1/CRM1-dependent nuclear export to induce apoptosis and autophagy in multiple myeloma.