Research Articles
Disarming Cancer's Command Center: A New Strategy to Halt Prostate Cancer
Discover how PLX-3618, a molecular degrader, is revolutionizing prostate cancer treatment by eliminating the BRD4 protein rather than just inhibiting it.
The Cellular Brake: How a PMEPA1 and NEDD4 Partnership Controls Prostate Cancer Growth
Discover how PMEPA1 and NEDD4-1 partnership controls androgen receptor degradation in prostate cancer through molecular mechanisms and therapeutic implications.
Cracking the Code of Treatment-Resistant Prostate Cancer: A Protein-Fueled Detective Story
Discover how proteomic profiling is revolutionizing our understanding of treatment-resistant prostate cancer and paving the way for personalized medicine approaches.
Molecular Glue Degraders: A Revolutionary Approach to Combat Treatment-Resistant Prostate Cancer
Discover how first-in-class molecular glue degraders target AR-V7 in treatment-resistant prostate cancer, offering new hope for patients.
The PMEPA1-NEDD4 Switch: How Prostate Cancer Cells Hijack Their Off Button
Discover how prostate cancer disables the PMEPA1-NEDD4 molecular brake system that regulates androgen receptor stability, leading to treatment resistance.
Silencing the Storm: How a Bone Drug Halts Prostate Cancer's Stealth Spread
New research reveals how Zoledronic acid dismantles EMT's machinery by targeting NEDD9, silencing prostate cancer's invasive voice.