Research Articles
Chromatin Relaxation: How a Lost Epigenetic Mark Opens New Doors in Ovarian Cancer Treatment
Discover how histone H2B monoubiquitination loss in ovarian cancer creates new therapeutic opportunities based on chromatin relaxation.
Beyond Enzymes: How Ring1B Redefines Genetic Control in Early Development
Discover how Ring1B's E3 ubiquitin ligase activity, once thought essential, is dispensable for early mouse development, reshaping our understanding of genetic regulation.
The Cellular Saboteur: How UHRF1 Drives Gastric Cancer's Deadly Spread
Explore how UHRF1 protein drives gastric cancer progression through epigenetic regulation, migration, invasion, and potential therapeutic targeting.
Unlocking the Vault: How a Cellular "Accomplice" Fuels Pancreatic Cancer's Drug Defenses
Discover how Histone Acetyltransferase 1 promotes gemcitabine resistance in pancreatic cancer through epigenetic regulation of the PVT1/EZH2 complex.
Unlocking the Genome: How Chromatin Modification Controls Our Genetic Destiny
Explore how chromatin modification regulates eukaryotic transcription and controls gene expression through epigenetic mechanisms.
Unlocking HIV's Hideout: How the Viral Protein Vpr Reshapes Epigenetics to Reignite Infection
Discover how HIV's Vpr protein hijacks host epigenetics to reactivate latent viral reservoirs, with implications for cure strategies.
Flickin' the Ubiquitin Switch: How a Tiny Protein Orchestrates Life's Symphony
Explore how ubiquitin, a small regulatory protein, controls cellular processes through precise molecular switches in DNA repair, immune responses, and gene expression.