Research Articles
UCHL1: The Cellular Architect Behind Neuroblastoma's Resilience
Exploring the role of Ubiquitin carboxyl-terminal esterase L1 (UCHL1) in neuroblastoma cancer stem-like cells and its therapeutic implications
A Botanical Assassin: How an Ancient Herb Tricks Cancer Cells into Self-Destructing
Discover how Oridonin from traditional Chinese medicine induces apoptosis in neuroblastoma cells by promoting Mdm2-p60 and activating p53-mediated pathways.
The Ubiquitin Switch: How a Molecular Tag Team Forces Cancer Cells to Self-Destruct
Discover how the UBE4B-ITCH complex induces neuroblastoma cell death through K63/K48 branched polyubiquitination of Ku70 and c-FLIPL, enhancing HDACi-mediated apoptosis.