Discover how inhibiting the 26S proteasome and K48-linked ubiquitination could revolutionize osteoarthritis treatment by targeting cellular waste management systems.
Discover how NLRP12 protein sabotages joint defenses in osteoarthritis by degrading NOD2 in synovial macrophages, revealing new treatment possibilities.
Discover how a ubiquitin-competitive strategy targeting the USP7 protein could revolutionize osteoarthritis treatment by addressing the cellular imbalance at its core.