Research Articles
The Body's Betrayal: Unraveling a Mystery in Pancreatic Cancer Wasting
Scientists investigate a suspected culprit in the devastating muscle loss that weakens pancreatic cancer patients, with surprising findings about the PDK4 enzyme.
Disarming the Body's Saboteur: How Silencing the ITCH Gene Could Revolutionize Pancreatic Cancer Treatment
Exploring how genetic knockdown of ITCH E3 ubiquitin ligase increases pancreatic cancer cell sensitivity to therapeutics through advanced gene-editing techniques.
Unlocking the Vault: How a Cellular "Accomplice" Fuels Pancreatic Cancer's Drug Defenses
Discover how Histone Acetyltransferase 1 promotes gemcitabine resistance in pancreatic cancer through epigenetic regulation of the PVT1/EZH2 complex.
Epigenetic Escape: How Losing KDM5A Fuels Pancreatic Cancer
Discover how the loss of KDM5A epigenetic regulator accelerates KRAS-driven pancreatic cancer progression and impacts treatment strategies.
The Cell's Garbage Disposal: How Pancreatic Cancer Hacks the System
Explore how pancreatic adenocarcinoma hijacks the Ubiquitin-Proteasome System and the innovative research fighting back against this formidable cancer.
The Stealth Saboteur: How Pancreatic Cancer Hijacks Muscle Maintenance via IGFBP-3
Groundbreaking research reveals how tumor-derived IGFBP-3 drives muscle wasting in pancreatic cancer patients through metabolic hijacking.