Explore how ubiquitination acts as a double-edged sword in coronavirus infections, serving both as a cellular defense mechanism and a viral replication tool.
Discover how complete ubiquitination machinery operates deep within the mitochondrial matrix through eclipsed distribution, rewriting our understanding of cellular biology.
Explore the emerging role of linear ubiquitination in cellular signaling, from immune response to organelle quality control and disease mechanisms.
Explore how ubiquitinated proteomics research using Hep3B cells is transforming our understanding of hepatocellular carcinoma and opening new therapeutic avenues.
Discover how murine Gbp1 and Gbp2 are ubiquitinated independently of Toxoplasma gondii infection, challenging our understanding of cellular defense mechanisms.
Discover how ubiquitination regulates circadian rhythms through precise protein tagging and degradation mechanisms in your body's biological clock.
Explore how ubiquitination acts as a master sorting signal in cellular endocytic pathways, directing protein traffic and degradation with profound implications for health and disease.
Discover how wheat germ cell-free systems revolutionized the study of ubiquitination, enabling high-sensitivity analysis of protein regulation mechanisms.
Discover how a single amino acid in RING E3 ubiquitin ligases controls cellular protein recycling and its implications for disease treatment.
Discover how ubiquitination regulates milk fat synthesis in dairy cows through molecular mechanisms that control fatty acid transport and triglyceride assembly.