Research Articles
Unlocking Cancer's Off Switch: How Stapled Peptides Target Rogue Proteins
Discover how multifunctional stapled peptides target β-catenin for ubiquitination and degradation, offering new hope for cancer treatment.
The Proteasomal Subunits: Unlocking New Frontiers in Cancer Therapy
Explore how proteasomal subunits are revolutionizing cancer therapy through targeted inhibition and overcoming drug resistance in various cancers.
Shattering Cancer's Defenses: The PROTAC Revolution Targeting MLK3
Discover how PROTAC technology is revolutionizing cancer therapy by targeting MLK3 in triple-negative breast cancer, offering hope against treatment-resistant tumors.
Molecular Staples: The Tiny Technology Taking Aim at Cancer's Command Center
Exploring how stapled alpha-helical peptides disrupt LUBAC to combat cancer by targeting the ubiquitin system.
The PEST Control Paradox: How a Tiny Protein Sequence Holds the Key to Cancer Therapy
Exploring how PEST sequences in nuclear proteins like PCNP regulate cancer progression and the therapeutic potential of targeting these mechanisms.
The Ubiquitin Assassins: How SCF E3 Ligases Became Cancer's Most Wanted Targets
Exploring how SCF E3 ubiquitin ligases function in cancer and the therapeutic strategies targeting these molecular complexes.
The p53 Puzzle: Decoding the Guardian's Secrets to Revolutionize Cancer Therapy
Exploring groundbreaking patents and therapies targeting the p53 protein to revolutionize cancer treatment.