Research Articles
The Genetic Blueprint of Frontotemporal Dementia: How Lost Messages in Neurons Reveal New Treatment Paths
Exploring the molecular genetics of frontotemporal dementia, including genetic causes, cellular mechanisms, and emerging treatments.
The Cell's Ultimate Shredder: How the Ubiquitin-Proteasome System Shapes Health, Aging, and Cancer
Explore the fascinating world of the ubiquitin-proteasome system - the cellular machinery that controls protein degradation and its crucial role in neurodegeneration, aging, and cancer.
The Cellular Cleanup Crew: How Protein Recycling Failures Drive Parkinson's Disease
Explore how failures in the ubiquitin-proteasome system contribute to Parkinson's disease pathology and potential therapeutic approaches.
The Protein Time Bomb: How Stroke Triggers a Hidden Neurodegenerative Cascade
Exploring the connection between stroke and neurodegenerative proteinopathies, including biomarkers and emerging treatments.
The Cellular Librarian: Isolating the Brain's Protein Recycling System
Discover how scientists are identifying the neuronal substrates of the ubiquitin-proteasome system and its implications for neurodegenerative diseases.
The Grape Defense: How Resveratrol Could Revolutionize Brain Health
Explore how resveratrol, a natural compound found in grapes and red wine, shows promise in fighting neurodegenerative diseases like Alzheimer's and Parkinson's through multiple protective mechanisms.
The Ubiquitin Saboteur: How a Mutant Protein Hijacks Cellular Cleanup in Neurodegeneration
Exploring how mutant UBB+1 protein hijacks cellular cleanup mechanisms in neurodegenerative diseases by targeting deubiquitinating enzymes (DUBs)
Decoding Complexity: How Systems Biology is Rewriting the Parkinson's Playbook
Explore how systems biology is transforming Parkinson's disease research through network analysis, multi-omics integration, and novel therapeutic approaches.
The Genetic Keys to Parkinson's: Unlocking the Secrets of Pathogenic Mutations
Exploring how pathogenic mutations reveal the biological underpinnings of Parkinson's disease and open new avenues for targeted therapies.