Research Articles
The Ubiquitin Switch: How a Molecular Tag Team Forces Cancer Cells to Self-Destruct
Discover how the UBE4B-ITCH complex induces neuroblastoma cell death through K63/K48 branched polyubiquitination of Ku70 and c-FLIPL, enhancing HDACi-mediated apoptosis.
Viral Betrayal: How a Pathogen's Sabotage Sparked a Diagnostic Revolution
How scientists turned a viral enzyme's sabotage of immune protein ISG15 into a powerful diagnostic tool for detecting infections.
The SUMO Switch: How Blocking a Tiny Cellular Tag Could Revolutionize Cancer Therapy
Discover how inhibiting SUMOylation with TAK-981 reprograms immune defenses and transforms cancer treatment by awakening macrophage and NK cell functions.
Unlocking the Heart's Shield: How a Surgical Sedative Fights Cardiac Injury Through Cellular Recycling
Discover how dexmedetomidine (Dex) protects against myocardial ischemia-reperfusion injury by activating cellular autophagy through the PINK1/Parkin pathway.
Calycosin's Cancer Breakthrough: How a Plant Compound Fights Kidney Cancer
Discover how calycosin, a plant-derived flavonoid, inhibits renal cell carcinoma by targeting the MAZ/HAS2 signaling pathway.
The Dark Particle: How a Brain Pigment Holds Clues to Parkinson's Disease
Exploring how neuromelanin organelles transform from cellular protectors to toxic agents in Parkinson's disease pathology.
The Silent Killers Within: Decoding Cancer, Aging and Inflammation at Cyprus' Premier Biomedical Congress
Coverage of the groundbreaking discoveries presented at the 6th International Multithematic Scientific Bio-Medical Congress in Cyprus, featuring Nobel Laureate Aaron Ciechanover and other leading researchers.
The Lethal Overdrive: How Supercharging Cancer Pathways Could Be Our Smartest Weapon Yet
Exploring how hyperactivating cancer pathways can be a novel synthetic lethality approach in oncology
MetaDegron: AI's Protein Prediction Powerhouse Reveals Cellular Recycling Secrets
Discover how MetaDegron's multimodal AI predicts cellular protein degradation signals (degrons) with unprecedented accuracy, opening new frontiers in drug discovery.
Chemoprevention: Your Cells' Ultimate Chill-Out Pill?
Explore the revolutionary frontier of cancer chemoprevention - a strategy that helps your cells stay cancer-free through natural compounds and repurposed drugs.