Discover how UHRF1 protein drives cancer progression in RB-mediated cancers through epigenetic mechanisms and experimental evidence
Discover how SIK2 inhibitor SIC-19 enhances PARP inhibitor sensitivity in triple-negative breast and pancreatic cancers through synthetic lethality approach.
Discover how UCHL1, SNRNP200, and PAK4 proteins create a molecular fingerprint that predicts kidney cancer aggressiveness and patient outcomes.
Discover how KRAS-mutant cancers use mitochondrial transfer to evade immune attacks and new therapeutic strategies to counter this biological warfare.
Discover how sea urchins defy aging with negligible senescence and what their biology reveals about longevity and healthspan.
Discover how creatine monohydrate protects chicken muscles from stress-induced breakdown by inhibiting the ubiquitin proteasome pathway.
Explore the fascinating process of DNA replication completion, telomeres, telomerase, and their implications for health and disease.
Discover how polyphyllins, natural compounds from Paris plants, are fighting cancer through multiple mechanisms including apoptosis, autophagy, and mitophagy.
Discover how scientists identify stable reference genes in the walnut pest Atrijuglans hetaohei using RT-qPCR analysis for accurate gene expression studies.
Explore the groundbreaking discovery of germline mosaicism in Angelman syndrome and how it transforms our understanding of genetic inheritance patterns.