Research Articles
Disarming Cancer's Master Switch: The Quest to Tame Rogue Wnt Signaling
How a clever new strategy of molecular jamming is taking aim at a notoriously undruggable pathway in cancer through novel peptides targeting the β-catenin/TBL1 complex.
The Cell's "Clutch" is Stuck: How a Tiny Molecular Switch Drives Lung Cancer
Discover how tyrosine phosphorylation of β-catenin drives drug resistance in EGFR-mutant lung cancer and the promising research behind this molecular mechanism.
How a Cellular Mischief-Maker Fuels Advanced Prostate Cancer Treatment Resistance
Discover how AKR1C3 and AR-V7 work together to create treatment resistance in advanced prostate cancer and the emerging therapeutic strategies to overcome this challenge.
The Leaky Nose: Unraveling a Hidden Culprit Behind Allergic Misery
Discover how MUC1 deficiency triggers nasal epithelial barrier dysfunction through RBFOX3 shortage and ubiquitin-proteasomal degradation in allergic rhinitis pathogenesis.
Taming Cellular Chaos: How a Molecular "Tag" Guides a Master Regulator of Cell Division
Discover how SUMOylation controls Polo-like Kinase 1 (Plk1) nuclear import and stability, revealing new insights into cell division and cancer therapy.
The Mind's Misfolding Proteins: The Battle to Diagnose Brain Diseases Before Autopsy
Exploring the diagnostic revolution for Frontotemporal Lobar Degeneration and Dementia with Lewy Bodies through advanced biomarkers and imaging technologies.
The Digital White Coat: How Technology is Revolutionizing Medicine
Explore how AI, telemedicine, robotics, and wearable technology are transforming healthcare delivery and improving patient outcomes.
The Cell's Ultimate Shredder: How the Ubiquitin-Proteasome System Shapes Health, Aging, and Cancer
Explore the fascinating world of the ubiquitin-proteasome system - the cellular machinery that controls protein degradation and its crucial role in neurodegeneration, aging, and cancer.
The Guardian's Betrayal: How BARD1 is Revolutionizing the Fight Against Breast Cancer
Discover how BARD1 gene research is transforming breast cancer screening, prevention, and treatment for predisposed women.
Disarming the Enemy Within: The New Era of Precision Strikes Against Leukemia
Explore how gene product-targeting therapy is revolutionizing leukemia treatment through precision medicine approaches.