Discover how SUMOylation stabilizes HNF4α protein to maintain liver function and its implications for metabolic diseases.
Explore how GPU-accelerated coarse-grained simulations with flexible linkers are revolutionizing our understanding of protein-protein interactions.
Explore how Cyclic Ion Mobility-Mass Spectrometry is transforming disease marker detection through advanced molecular separation technology.
Discover how EZH2 inhibition unexpectedly enhances PD-L1 protein stability through USP22-mediated deubiquitination in colorectal cancer, revealing new therapeutic strategies.
Explore how transgenic mice with ubiquitous mCherry expression are revolutionizing biological research through fluorescent protein technology.
Discover how SUMOylation regulates telomere length by targeting Tpz1 to control shelterin-Stn1 interaction in fission yeast and its implications for human health.
Explore how pancreatic adenocarcinoma hijacks the Ubiquitin-Proteasome System and the innovative research fighting back against this formidable cancer.
Discover how the overlooked Histone H3 protein directs BRCA1/BARD1 in DNA repair, revealing new insights into cancer prevention mechanisms.
Explore the role of USP22 gene in cancer progression, prognosis, and potential therapeutic targeting in this comprehensive scientific overview.
Discover how scientists use transient expression to screen promoters for creating genetically modified anthuriums with novel traits like unique colors and disease resistance.