Research Articles
The Invisible Switch: How a Tiny Genetic Variation Shapes Your Cancer Risk
Discover how MDM4 SNP34091 (rs4245739) influences cancer risk across different types through microRNA regulation of the p53 pathway.
The Autophagy Key: Unlocking Diabetic Wound Healing with Ancient Wisdom
Exploring how Traditional Chinese Medicine modulates autophagy to heal diabetic wounds through cellular mechanisms and ancient wisdom.
The Invisible Editors of Cancer: How Ubiquitin-Specific Proteases Rewrite Our Understanding of Tumors
Recent research reveals USPs as master regulators of tumor survival, metastasis, and drug resistance, making them prime targets for next-generation therapies.
The Nucleolus Unmasked: How a Cellular Factory Became Cancer's Achilles Heel
Groundbreaking research reveals the nucleolus plays a critical role in triple-negative breast cancer (TNBC) and how innovative tools like the Auxin-Inducible Degron system are uncovering new therapeutic targets.
The NEDD4-JNK Connection: Decoding Chemoresistance in Colorectal Cancer
Discover how NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer through JNK signaling pathway modulation.
The SUMO Surprise: How a Tiny Protein Could Revolutionize Heart Failure Treatment
Discover how the SUMO-1 protein is transforming heart failure treatment through groundbreaking research and gene therapy.
Double Punch Against Resistant Cancer: New Hope for Aggressive Breast Tumors
How blocking two cellular cleanup crews together overcomes drug resistance in tough-to-treat breast cancer.
The TRIM16 Enigma: How a Cellular Watchdog Tames Breast Cancer's Most Dangerous Cells
Exploring the role of TRIM16 in suppressing breast cancer stem cells through Gli-1 degradation via the ubiquitin-proteasome pathway
Unlocking the Developmental Secrets of a Global Disease Vector: The Transcriptomic Journey of Triatoma rubrofasciata
Transcriptomic analysis of Triatoma rubrofasciata, a vector of Chagas disease, across seven developmental stages revealing key genetic insights for vector control.
The Silent Guardian: How FBXO11's Disappearance Fuels a Deadly Blood Cancer Transformation
Discover how FBXO11 acts as a tumor suppressor in the transformation of MDS to secondary AML, with groundbreaking research revealing its critical role in blood cancer progression.