Research Articles
HSN-003839: Harnessing the Body's Cellular Recycling System to Target Cancer
Explore HSN-003839, a novel USP21 inhibitor showing promise in cancer therapy by targeting the ubiquitin-proteasome system.
Cracking the Code of Muscle Waste: How Gene Mapping is Revolutionizing Treatment for Atrophy
Discover how transcriptional profiling is revolutionizing our understanding of skeletal muscle atrophy and leading to new therapeutic approaches.
How a Cellular Miscreant Drives Childhood Bone Cancer: The A1BG-AS1 Story
Discover how the long non-coding RNA A1BG-AS1 promotes osteosarcoma progression through molecular mechanisms and potential therapeutic targets.
Unlocking a Locked Door: The Quest to Fix Cystic Fibrosis's Root Cause
Explore the scientific journey to improve Delta F508 CFTR surface expression in cystic fibrosis treatment through innovative research and therapies.
When Cell Biology Meets Development: The Hidden Regulator Within
Exploring how endocytosis regulates developmental signaling pathways, from cellular processes to embryonic development.
The Ubiquitin System: The Cell's 'Shredder' and Its Promise as a Lung Cancer Target
Explore how the ubiquitin system functions as the cell's protein disposal mechanism and its emerging role as a therapeutic target in lung cancer treatment.
Breaking the Shield: How RAD6 Inhibition Makes Triple-Negative Breast Cancer Vulnerable to Therapy
Discover how RAD6 inhibition sensitizes triple-negative breast cancer to platinum-based therapy, offering new hope for TNBC patients.
Spatial Maps of the Brain: Decoding Epilepsy's Secrets with Spatial Transcriptomics
Explore how spatial transcriptomics is revolutionizing our understanding of focal cortical dysplasia type IIb and drug-resistant epilepsy through molecular mapping of brain tissues.
The Silent Thief of Words: Understanding Language and Communication in Alzheimer's Disease
Exploring how Alzheimer's disease progressively impacts language and communication, with research-backed strategies for maintaining connection.
The Broken Brake: How a Strange New Protein Fuels Glioblastoma
Discover how rolling-translated EGFR variants sustain signaling in glioblastoma through circular RNA mechanisms and their clinical implications.