Research Articles
Nature's Weight Loss Supplement Has a Hidden Cost: How Berberine Impacts Muscle Health
Explore how berberine, a popular weight loss supplement, affects muscle metabolism through Atrogin-1 activation and its implications for muscle health.
Breaking the Shield: How a Novel Compound Forces Lung Cancer Cells to Self-Destruct
Discover how SHetA2 overcomes lung cancer resistance by down-regulating c-FLIP and survivin to enhance TRAIL-induced apoptosis.
The 1q Amplification in Multiple Myeloma: A Genetic Key to More Aggressive Cancer
Understanding how 1q amplification drives aggressive multiple myeloma and the search for targeted therapies
The Silent River of Salt: Unlocking a Genetic Secret to Blood Pressure Control
Discover how the Usp2 gene inactivation reveals new pathways in blood pressure regulation and sodium balance maintenance.
The Silent Sabotage: How Metabolic Syndrome Disrupts Your Cellular Machinery
Explore how metabolic syndrome disrupts cellular function through redox imbalance and proteasomal dysfunction, and discover emerging therapeutic approaches.
Cellular Matchmaking: How the MYTH System Sniffs Out Protein Partners
Discover how the Split-Ubiquitin Membrane Yeast Two-Hybrid (MYTH) system revolutionizes our understanding of membrane protein interactions and cellular communication networks.
Unlocking the Genome: How Chromatin Modification Controls Our Genetic Destiny
Explore how chromatin modification regulates eukaryotic transcription and controls gene expression through epigenetic mechanisms.
To Kill or to Be Killed: How Does the Battle between the UPS and Autophagy Maintain the Intracellular Homeostasis in Eukaryotes?
Explore the intricate battle between the Ubiquitin-Proteasome System (UPS) and autophagy in maintaining cellular homeostasis and preventing diseases.
The Cell's Broken Garbage Disposal: How It Creates Superbugs
Discover how a fault in fission yeast's proteasome creates multi-drug resistant superbugs by stabilizing the Pap1 transcription factor.
Unlocking Cancer's Off Switch: How Stapled Peptides Target Rogue Proteins
Discover how multifunctional stapled peptides target β-catenin for ubiquitination and degradation, offering new hope for cancer treatment.