Research Articles
The COP9 Signalosome: The Heart's Molecular Conductor
Explore the intricate relationship between the COP9 signalosome and cullin-RING ligases in maintaining cardiac health through protein regulation.
The Cellular Orchestra: How Ubiquitin Pulls the Strings of the Hippo Pathway
Explore how ubiquitin modification regulates the Hippo signaling pathway, controlling organ size and influencing cancer development through sophisticated molecular mechanisms.
The Molecular Puppet Master: How Scientists Uncovered miR-21's Hidden Network in Liver Cancer
Discover how Argonaute-CLIP analysis revealed miR-21's extensive network in liver cancer, uncovering novel therapeutic targets and mechanisms.
Breaking Bad Proteins: How Scientists Are Hijacking Mitochondrial Cleanup Crews to Control Cellular Health
Discover how targeted protein degradation in mitochondria is revolutionizing our approach to treating diseases linked to mitochondrial dysfunction.
The Cell's Unsung Hero: How a Molecular Shredder Fights Cancer
Discover RNF144B, a newly discovered molecular shredder that prevents genomic instability and fights cancer as part of the p53 tumor suppressor pathway.
The Plant's Secret Switch: How a Whiff of Sulfur Keeps Leaves Alive
Discover how plants use sulfur-based molecular switches called persulfidation to adapt to light/dark cycles and survive carbon deprivation.
Lipid Signaling: The Molecular Language of Life and Disease
Explore the fascinating world of lipid signaling, PI3K pathways, and their crucial role in health and disease, including cancer therapeutics.
Cracking Cancer's Invasion Code: How a Cellular Switch Drives Colorectal Cancer Spread
Discover how the MEK/ERK-ZEB1-USP10 pathway controls colorectal cancer metastasis and the therapeutic implications of this molecular switch.
Unlocking the Immune System: How a Novel Cancer Therapy Boosts Fight Against Lymphoma
Explore how NEDD8-activating enzyme inhibitors transform lymphoma treatment by enhancing anti-tumor immunity and synergizing with PD-1 checkpoint blockade.
The Cellular Tug-of-War: How Tiny Enzymes Decide Life or Death
Explore how E3 ubiquitin ligases and deubiquitinases control the TRAIL-mediated apoptosis pathway in this engaging scientific article.