Discover how non-toxic fractions from Streptomyces hygroscopicus show promising antimalarial properties by targeting the PfMQO mitochondrial enzyme in malaria parasites.
Discover how hepatocyte-derived exosomes transport drug-modified proteins to immune cells, triggering idiosyncratic drug-induced liver injury (DILI).
Discover how Hepatitis B virus manipulates host protein interactions to create cellular dependencies and ensure its survival, with implications for new therapeutic approaches.
Discover how functional interaction network analysis is transforming cattle breeding by identifying key genes responsible for reproductive traits.
Discover how omega-3 nanoemulsion protects kidneys from colistin antibiotic damage by regulating autophagy and necroptosis pathways.
Discover how GPCR activation regulates WWP2 through CDH1 to mediate ALIX-dependent lysosomal sorting in this engaging popular science article.
Discover how ALIX and PAR1 challenge our understanding of cellular sorting mechanisms through a ubiquitin-independent pathway.
Discover how FRMD3 protein suppresses breast cancer progression by targeting vimentin for degradation through the ubiquitin-proteasome system.
Discover how UCHL1 overexpression induces apoptosis in breast cancer cells, particularly triple-negative breast cancer, offering new therapeutic approaches.
Scientists discover a surprising new protector protein that could lead to innovative treatments for renal clear cell carcinoma.