Research Articles
Unleashing the Immune System: How Cbl-b Deficiency Makes T Cells Resistant to Cancer's Brakes
Discover how Cbl-b deficiency makes T cells resistant to PD-L1-mediated inhibition and its implications for cancer immunotherapy.
UBR5: The Cellular Conductor Turned Cancer Villain
Explore the dual role of UBR5 E3 ubiquitin ligase in cancer progression and suppression, its mechanisms, and therapeutic targeting strategies.
The Master Key: Unlocking Your Body's Blueprint from Stem Cells
Discover how scientists identified the TBX6 protein as a master regulator that commands stem cells to become muscle, bone, and heart tissue.
How a Single Gene Helps Plants Beat Drought and Manage Flowering Time
Discover how overexpression of the GmUBC9 gene enhances plant drought resistance and affects flowering time through histone H2B monoubiquitination.
Claspin: The Genome's Guardian and Its Battle Against Cancer
Explore the fascinating role of Claspin protein in DNA replication, checkpoint signaling, and its implications in cancer development and treatment.
The Silent Mutation: How a Tiny Genetic Change Accelerates Motor Neuron Disease
Discover how the OPTN-K489E mutation disrupts cellular balance and accelerates ALS progression through enhanced apoptosis, necroptosis, and autophagy pathways.
Frog Testes and Cellular Secrets: Decoding Ubiquitin through cDNA Libraries
Exploring how cDNA libraries from frog testes reveal insights into the ubiquitin system and its role in cellular regulation and human health.
The Invisible Shield: How a Tiny Protein Could Revolutionize Radiation Therapy for Lung Cancer
Discover how tristetraprolin (TTP) mediates radiation-induced TNF-α production in lung macrophages and its potential to revolutionize lung cancer treatment.
The Ubiquitin Code: How a Tiny Protein Dictates Wound Healing
Discover how ubiquitin, a tiny protein, regulates the complex process of wound healing through ubiquitination, acting as a cellular maestro in tissue repair and regeneration.
Cracking Citrus' Genetic Code: How Mandarin Trees Avoid Dating Themselves
Discover how scientists use transcript profiling to understand self-incompatibility in mandarins and create seedless varieties through advanced genetic research.