Research Articles
The Unseen War in Your Joints: How a Rogue Protein Fuels Arthritis
Discover how NLRP12 protein sabotages joint defenses in osteoarthritis by degrading NOD2 in synovial macrophages, revealing new treatment possibilities.
The Unseen Battle Within: How a Cellular Conductor Orchestrates Heart Inflammation
Discover how the E3 ubiquitin ligase COP1 regulates macrophage inflammation in sepsis-induced myocardial injury through ubiquitination of C/EBPβ.
The Cellular Switch: How Nedd4 Controls Muscle Fate by Targeting Notch1
Discover how Nedd4 regulates Notch1 in muscle atrophy and its implications for cellular biology and therapeutic development.
Cracking FTD's Code: How Scientists Are Deciphering TDP-43's Deadly Patterns
Discover how a harmonized classification system is revealing the secrets of frontotemporal dementia by linking TDP-43 protein patterns to specific symptoms and genetic causes.
A Wolf in Sheep's Clothing: Can a "Growth" Drug Starve Cancer?
Scientists are investigating a surprising new weapon in the fight against cancer using Ibutamoren, a drug that exploits the body's anti-cancer systems.
The KLHL Family: The Cellular Cleanup Crew Gone Rogue in Cancer
How tiny protein regulators in our cells hold the key to new cancer treatments. Explore the role of KLHL proteins in cancer development and progression.
Cellular Hide and Seek: How Leukemia Cells Use Tiny Bubbles to Resist Chemotherapy
Discover how exosomal miR-196a-5p helps acute myeloid leukemia cells resist chemotherapy through ferroptosis inhibition in the bone marrow microenvironment.
The Cellular Stress Symphony: How Heat Shock Proteins Respond to Normalized Blood Sugar in Type 2 Diabetes
Explore how heat shock proteins respond to normalized blood sugar in type 2 diabetes, revealing insights into cellular stress responses and potential therapeutic applications.
Green Armor for Corn: How Genetic Engineering Is Creating Insect-Resistant Maize
Explore how Agrobacterium-mediated genetic transformation creates insect-resistant maize using Bt proteins like Cry1Ab and Cry1Ac to combat agricultural pests.
The Accidental Hero: How an Old Arthritis Drug Supercharges a Cellular Cleanup Crew
Discover how Auranofin, an old arthritis drug, enhances UBA1 activity and facilitates ubiquitin trans-thioesterification to E2 enzymes, opening new frontiers in disease treatment.