Research Articles
The Linchpin Discovery: How a Single Amino Acid Controls the Cell's Recycling Machinery
Discover how a single amino acid in RING E3 ubiquitin ligases controls cellular protein recycling and its implications for disease treatment.
The Double-Edged Sword of Immunity: Engineering a Key Monkey Protein
Discover how scientists engineered bioactive rhesus monkey TNF-α using SUMO fusion technology to advance medical research.
Cellular Guardians: The Molecular Editors That Maintain Your Body's Architecture
Discover how deubiquitylases protect cellular junctions and maintain tissue integrity, with implications for cancer and inflammatory disease treatments.
The Cellular Tug-of-War: How a Tiny Protein Tames a Growth Giant
Discover how the HILI protein inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation in this groundbreaking cancer research.
The Silent Enemy Within: How EXOSC3 Worsens Oral Cancer
Discover how the EXOSC3 protein transforms from cellular housekeeper to cancer accomplice in oral squamous cell carcinoma, affecting prognosis and immune response.
A Botanical Assassin: How an Ancient Herb Tricks Cancer Cells into Self-Destructing
Discover how Oridonin from traditional Chinese medicine induces apoptosis in neuroblastoma cells by promoting Mdm2-p60 and activating p53-mediated pathways.
Unlocking a Cancer's Weakness: The Protein Disposal Dilemma
Discover how Velcade targets cancer cells by inhibiting proteasome function, forcing them into apoptosis through protein waste accumulation.
The Molecular Puppeteer: How ZC3H15 Protein Drives Deadly Brain Cancer
Discover how the ZC3H15 protein regulates EGFR stability to promote glioblastoma progression in this groundbreaking cancer research article.
When Inhaled Particles Haunt the Mind: The Unseen Journey of Zinc Oxide Nanoparticles to the Brain
Exploring how inhaled zinc oxide nanoparticles travel from lungs to brain and their neurological effects
The Hidden Factory Within: How Scientists Discovered a Cellular Control System Operating Inside Mitochondria
Discover how scientists found ubiquitination occurring inside mitochondria, rewriting our understanding of cellular control systems.