Research Articles
Cecile Pickart: The Maestro of Ubiquitin and Cellular Symphony
Explore the groundbreaking work of Cecile Pickart, who decoded the language of ubiquitin and revolutionized our understanding of cellular regulation.
The Pear's Secret Code: Finding the Constant in a Changing Fruit
Discover how scientists systematically validate reference genes to ensure accurate gene expression studies in pears, from sweetness to disease resistance.
The Cellular Key: How Protein Degradation Unlocks Plant Root Development
Discover how APC-targeted RAA1 degradation regulates cell cycle progression and root architecture in plants through the ubiquitin-proteasome system.
The Genetic Detectives: How Querétaro Scientists Are Unraveling the Mystery of Cleft Lip and Palate
Discover how Querétaro researchers are validating IRF6 and SUMO1 as genetic markers for non-syndromic cleft lip and palate in the local population.
The Hidden Guardian: How a Tiny Protein Could Revolutionize Brain Cancer Treatment
Discover how FBXO8, a tiny protein, correlates with tumor grade and prognosis in human glioma, offering new hope for brain cancer treatment.
Breaking the Shield: Targeting Cellular Waste Management for Ovarian Cancer Treatment
Exploring how targeting deubiquitinating enzymes (DUBs) associated with the proteasome could revolutionize ovarian cancer treatment by overcoming drug resistance.
The Genome's Dance Partners: How DUB/USP17 Enzymes and Beta-Defensins Perform a Delicate Genetic Tango
Exploring the fascinating relationship between DUB/USP17 deubiquitinating enzymes and the beta-defensin cluster in human genetics and disease.
Predicting Recovery: How Brain Biomarkers Are Revolutionizing Traumatic Brain Injury Treatment
Explore how predictive biomarkers are transforming the diagnosis and treatment of traumatic brain injury, improving patient outcomes through personalized medicine.
The Hidden Driver of Colitis: How Multi-Omics Uncovered a New Therapeutic Target
Discover how multi-omics research identified p21-activated kinase signaling as a key driver of colitis, opening new therapeutic possibilities for inflammatory bowel disease.
Unleashing the Immune System: How Cbl-b Deficiency Makes T Cells Resistant to Cancer's Brakes
Discover how Cbl-b deficiency makes T cells resistant to PD-L1-mediated inhibition and its implications for cancer immunotherapy.