Nano-Revolution: Dual-Action Particles Are Rewriting Osteosarcoma's Rules
How dual-functional nanoplatforms are transforming osteosarcoma treatment by modulating the tumor microenvironment and activating immune responses.
Featured Research
Unlocking Cancer's Shape-Shifting Secret: How a Single Protein Pulls the Strings in Ewing Sarcoma
Discover how EWS-FLI1 orchestrates Ewing sarcoma plasticity through a post-translational modification cascade regulating FOXM1 stability.
The Genetic Goldmine: Unlocking Bali Cattle's Potential Through Myostatin Secrets
Exploring how myostatin promoter polymorphisms could revolutionize Bali cattle breeding programs through enhanced muscling and fat deposition traits.
The Dark Particle: How a Brain Pigment Holds Clues to Parkinson's Disease
Exploring how neuromelanin organelles transform from cellular protectors to toxic agents in Parkinson's disease pathology.
The Proteasome's Achilles' Heel: How Targeting RPN13 Could Revolutionize Ovarian Cancer Treatment
Exploring RPN13 as a novel therapeutic target for ovarian cancer treatment, focusing on its role in the proteasome system and potential to overcome chemotherapy resistance.
The Lethal Overdrive: How Supercharging Cancer Pathways Could Be Our Smartest Weapon Yet
Exploring how hyperactivating cancer pathways can be a novel synthetic lethality approach in oncology
Molecular Scissors That Reshaped Biology: How FAK-Targeting PROTACs Revealed Hidden Functions of a Key Protein
Discover how PROTAC technology revolutionized our understanding of FAK protein's non-enzymatic functions in fertility and cancer research.
The Ubiquitin Switch: How a Molecular Tag Team Forces Cancer Cells to Self-Destruct
Discover how the UBE4B-ITCH complex induces neuroblastoma cell death through K63/K48 branched polyubiquitination of Ku70 and c-FLIPL, enhancing HDACi-mediated apoptosis.
Calycosin's Cancer Breakthrough: How a Plant Compound Fights Kidney Cancer
Discover how calycosin, a plant-derived flavonoid, inhibits renal cell carcinoma by targeting the MAZ/HAS2 signaling pathway.
The Ubiquitin Enigma: How a Tiny Protein in Silkworms Holds Keys to Cellular Secrets
Exploring the critical role of BmUBRPS27a ubiquitin protein in silkworm development, immunity, and silk production
The Molecular Scissors Fueling Esophageal Cancer: How SENP5 Hijacks Cellular Machinery to Drive Tumor Growth
Discover how SENP5 promotes esophageal squamous cell carcinoma growth through the NF-κB-SLC1A3 axis and its potential as a therapeutic target.
The Silent Guardian: How FBXO11's Disappearance Fuels a Deadly Blood Cancer Transformation
Discover how FBXO11 acts as a tumor suppressor in the transformation of MDS to secondary AML, with groundbreaking research revealing its critical role in blood cancer progression.
Latest Discoveries
Aug 09, 2025
MetaDegron: AI's Protein Prediction Powerhouse Reveals Cellular Recycling Secrets
Discover how MetaDegron's multimodal AI predicts cellular protein degradation signals (degrons) with unprecedented accuracy, opening new frontiers in drug discovery.
By James Parker
Aug 09, 2025
The Dark Particle: How a Brain Pigment Holds Clues to Parkinson's Disease
Exploring how neuromelanin organelles transform from cellular protectors to toxic agents in Parkinson's disease pathology.
By Aurora Long
Aug 09, 2025
Unlocking p53's Potential: The Gene Signature Predicting Cancer Drug Success
Discover how a 13-gene signature predicts response to MDM2 inhibitors in p53 wild-type cancers, enabling personalized therapy approaches.
By Mia Campbell
Aug 09, 2025
Chemoprevention: Your Cells' Ultimate Chill-Out Pill?
Explore the revolutionary frontier of cancer chemoprevention - a strategy that helps your cells stay cancer-free through natural compounds and repurposed drugs.
By Genesis Rose
Aug 09, 2025
The Silent Killers Within: Decoding Cancer, Aging and Inflammation at Cyprus' Premier Biomedical Congress
Coverage of the groundbreaking discoveries presented at the 6th International Multithematic Scientific Bio-Medical Congress in Cyprus, featuring Nobel Laureate Aaron Ciechanover and other leading researchers.
By Mia Campbell
Aug 09, 2025
Unlocking Nature's Arsenal: How an Ancient Malaria Drug Targets Aggressive Ovarian Cancer
Discover how dihydroartemisinin (DHA), derived from ancient antimalarial plants, targets PDGFRα in aggressive ovarian cancer, offering new hope against this lethal disease.
By Aria West
Aug 09, 2025
The Lethal Overdrive: How Supercharging Cancer Pathways Could Be Our Smartest Weapon Yet
Exploring how hyperactivating cancer pathways can be a novel synthetic lethality approach in oncology
By Aiden Kelly
Aug 09, 2025
The p53 Puzzle: Decoding the Guardian's Secrets to Revolutionize Cancer Therapy
Exploring groundbreaking patents and therapies targeting the p53 protein to revolutionize cancer treatment.
By Sofia Henderson
Aug 09, 2025
Unlocking Cancer's Shape-Shifting Secret: How a Single Protein Pulls the Strings in Ewing Sarcoma
Discover how EWS-FLI1 orchestrates Ewing sarcoma plasticity through a post-translational modification cascade regulating FOXM1 stability.
By Grayson Bailey
Aug 09, 2025
The Secret Weapons in Banana Sap: How Proteins Are Fighting a Deadly Fungus
Discover how proteomic analysis of banana xylem sap reveals resistance mechanisms against Fusarium oxysporum TR4, the deadly banana fungus threatening global production.
By Charles Brooks
Aug 09, 2025
The Metabolic Maestro: How PKM2 and Matrin 3 Orchestrate a Cancer Symphony
Exploring how PKM2 phosphorylates Matrin 3 to promote FOXC2-mediated tumorigenesis in cancer metabolism.
By Isaac Henderson
Aug 09, 2025
The Cancer Drug That Could Rescue Brains: How Bortezomib Offers New Hope for a Rare Genetic Disorder
Discover how bortezomib, a cancer drug, shows promise in treating Niemann-Pick Type C disease by rescuing misfolded NPC1 proteins and reducing cholesterol accumulation.
By Julian Foster
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