Research Articles
The Cell's Hitman: How Our Body Marks a Key SARS-CoV-2 Protein for Destruction
Discover how our cells use the CRL4B-PRPF19 complex to target SARS-CoV-2 ORF6 protein for destruction, revealing new antiviral therapeutic strategies.
The Cellular Shredder: How a "Quality Control" Glitch Sparks Tumors
Discover how rapid proteasomal degradation of mutant AIP proteins triggers tumor formation in hereditary cancer syndromes.
Cellular Cities and Cancer: What Fruit Flies Teach Us About Keeping Order in Our Tissues
Discover how fruit fly research reveals the connection between cellular structure and cancer through tumor suppressor genes and epithelial polarity.
The Ubiquitin Architects: How TRIM Proteins Shape Metabolic Health
Discover how TRIM proteins function as cellular regulators influencing insulin resistance and metabolic disorders through ubiquitination pathways.
The Cell's Demolition Crew: How Scientists Are Teaching Our Bodies to Destroy "Undruggable" Proteins
Discover how the groundbreaking PROTINb platform uses targeted protein degradation to eliminate previously 'undruggable' proteins causing diseases like cancer and neurodegenerative disorders.
Taming the Fire Within: How a Low-Protein Diet Calms Rheumatoid Arthritis
Discover how a low-protein diet reprograms immune cells to reduce inflammation in Rheumatoid Arthritis through the NRF2/SIRT3/SOD2 pathway.
When Mind and Muscle Fail: The Surprising Connection Between ALS and Frontotemporal Dementia
Exploring the overlapping characteristics of amyotrophic lateral sclerosis and frontotemporal dementia, from genetics to clinical manifestations.
The Cellular Betrayal: How a Rogue Protein Hijacks Our Body's Cancer Defense
Discover how the SS18-SSX1 oncoprotein promotes cancer by hijacking the p53 tumor suppressor pathway through enhanced HDM2 stability.
Hitting Undruggable: The Protein Assassins Revolutionizing Medicine
Explore the revolutionary world of targeted protein degradation and how PROTACs are transforming medicine by destroying disease-causing proteins.
The Cell's Secret Weapon: How a Tiny Protein Supercharges Our Immune Defense
Discover how JAB1 protein amplifies interferon response and revolutionizes our understanding of immune defense against viruses and diseases.