Discover how colon cancer cells manipulate the p21 pathway through Activin, PI3K, NF-κB and MDM2 to promote metastasis.
Discover how RING-H2 finger E3 ligases regulate cotton fiber development and stress responses through genome-wide analysis of Gossypium species.
Discover how CDK7 and CDK9 kinases prime cancer cells for paraptosis, an alternative cell death pathway that could revolutionize cancer treatment.
Explore how Solid-State NMR spectroscopy reveals atomic-level details of crystalline, membrane-embedded, and fibrillar proteins that are inaccessible to other techniques.
Exploring how pathogenic mutations reveal the biological underpinnings of Parkinson's disease and open new avenues for targeted therapies.
Exploring how deubiquitinating enzyme inhibitors could revolutionize cervical cancer treatment by targeting the cell's protein recycling system.
Discover how GSK-3β inhibitors protect hippocampal neurons from radiation-induced apoptosis through MDM2/p53 pathway regulation.
Exploring the molecular blueprint of locust development through the lens of LmUBX2, revealing potential vulnerabilities in one of humanity's oldest agricultural adversaries.
Exploring the fascinating world of intrinsically disordered proteins (IDPs) and their revolutionary impact on medicine and biology.
Explore the revolutionary protein degradation therapies entering clinical trials for cancer treatment, offering new hope against 'undruggable' targets.