Emerging science reveals how repetitive head impacts in sports leave lasting molecular signatures detectable in blood biomarkers, offering early warning for neurological risks.
Discover how VRK2 protein promotes liver cancer metastasis by stabilizing ATG5 and activating autophagy-mediated degradation of ZO-1 tight junctions.
Discover how USP44 regulates chemoresistance through ROS and the MAPK/NF-κB pathway by stabilizing ITGB4 in gastric cancer.
Discover how scientists are using CRISPR-loaded extracellular vesicles as Trojan horses to target and destroy osteosarcoma bone cancer cells with precision.
Explore the science behind protein aggregation in neurodegenerative diseases like Alzheimer's and Parkinson's, and discover groundbreaking research on potential treatments.
Discover how UBE2T-mediated HP1α ubiquitination enhances nucleolar function and drives the progression of IDH1/TP53-mutant glioma in this comprehensive scientific exploration.
Explore the complex relationship between Chronic Kidney Disease and increased thrombosis risk, including scientific research, diagnostic tools, and treatment approaches.
Discover how TRAF7 inhibits esophageal cancer by degrading SOX12 through the ubiquitin-proteasome system in this comprehensive scientific article.
Explore the revolutionary PROTAC technology targeting CDKs for breast cancer treatment - from inhibition to complete protein degradation.
Discover how microsporidia parasites cleverly hijack cellular autophagy to promote their own growth in mammalian cells.