Discover how calycosin, a plant-derived flavonoid, inhibits renal cell carcinoma by targeting the MAZ/HAS2 signaling pathway.
Exploring how neuromelanin organelles transform from cellular protectors to toxic agents in Parkinson's disease pathology.
Coverage of the groundbreaking discoveries presented at the 6th International Multithematic Scientific Bio-Medical Congress in Cyprus, featuring Nobel Laureate Aaron Ciechanover and other leading researchers.
Exploring how hyperactivating cancer pathways can be a novel synthetic lethality approach in oncology
Explore the revolutionary frontier of cancer chemoprevention - a strategy that helps your cells stay cancer-free through natural compounds and repurposed drugs.
Discover how MetaDegron's multimodal AI predicts cellular protein degradation signals (degrons) with unprecedented accuracy, opening new frontiers in drug discovery.
Discover how bortezomib, a cancer drug, shows promise in treating Niemann-Pick Type C disease by rescuing misfolded NPC1 proteins and reducing cholesterol accumulation.
Discover how EWS-FLI1 orchestrates Ewing sarcoma plasticity through a post-translational modification cascade regulating FOXM1 stability.
Discover how a 13-gene signature predicts response to MDM2 inhibitors in p53 wild-type cancers, enabling personalized therapy approaches.
Exploring how PKM2 phosphorylates Matrin 3 to promote FOXC2-mediated tumorigenesis in cancer metabolism.